1-(Benzyloxy)-2,3-dinitrobenzene → 3-(Benzyloxy)benzene-1,2-diamine

HRID 1030520ノート

反応式

HRID 1030520 の反応式
[CH2:1]([O:8][C:9]1[C:10]([N+:18]([O-])=O)=[C:11]([N+:15]([O-])=O)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H][H]>C(O)C.[Ni]>[CH2:1]([O:8][C:9]1[C:10]([NH2:18])=[C:11]([NH2:15])[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

4

反応物 2

HCID 139713581-(Benzyloxy)-2,3-dinitrobenzeneHCID 178418361HCID 178418361、化合物

生成物 1

HCID 44012883-(Benzyloxy)benzene-1,2-diamine収率 102.3%

試薬・触媒・溶媒 1

HCID 86745698ethanol Raney-nickel溶媒

実験手順

To a solution of 3-benzyloxy-1,2-dinitrobenzene (2 g, 0.0073 mol) in 300 ml ethanol Raney-nickel (1 g) was added and the mixture was hydrogenated at room temperature and atmospheric pressure until the uptake of hydrogen ceased (30 min). The colourless solution was filtered (celite) and evaporated to dryness in vacuo to give the title compound as an unstable oil (1.6 g) which was used immediately for the next step.

後処理

  1. customwas hydrogenated at room temperature
  2. custom(30 min)
  3. filtrationThe colourless solution was filtered (celite)
  4. customevaporated to dryness in vacuo

出典と根拠

ORDレコード
ord-c18ccd15a23a4d11834ee6c982afc680
出典データセット
uspto-grants-1992_04
特許番号
US05106862

反応ノート

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