HCID 14078470、化合物 → 4-Methoxybenzaldehyde

HRID 1030703ノート

反応式

HRID 1030703 の反応式
O[C:2]1[C:7](CC=C(C)C)=[C:6]([O:13][CH3:14])[CH:5]=[CH:4][C:3]=1[C:15](=[O:17])C>C(O)C>[CH:15](=[O:17])[C:3]1[CH:2]=[CH:7][C:6]([O:13][CH3:14])=[CH:5][CH:4]=1

参加物

3

反応物 1

HCID 14078470HCID 14078470、化合物

生成物 1

HCID 312444-Methoxybenzaldehyde

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

In 5 ml of ethanol were dissolved 0.4 g of the 2'-hydroxy-4'-methoxy-3'-(3-methyl-2-butenyl)acetophenone obtained in Production Example 2 and 0.3 ml of p-anisaldehyde, and the solution was cooled to 0° C. and 7.5 ml of a saturated solution of potassium hydroxide in ethanol was added to the solution. In a nitrogen current, the mixture was stirred at 0° C. for 30 minutes and at room temperature for 4 days. After the reaction, hydrochloric acid was added to the reaction liquid under cooling and the reaction liquid was gradually made acidic, and the formed precipitate was recovered by filtration and recrystallized from methanol to obtain 0.4 g (yield=64.7%) of 2'-hydroxy-4,4'-dimethoxy3'-(3-methyl-2-butenyl)chalcone in the form of a yellow needle.

出典と根拠

ORDレコード
ord-fb9a71f8818b4f179a593cac0cb31f70
出典データセット
uspto-grants-1992_04
特許番号
US05106871

反応ノート

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