HCID 14078470、化合物 → 4-Methoxybenzaldehyde

HRID 1030735ノート

反応式

HRID 1030735 の反応式
O[C:2]1[C:7](CC=C(C)C)=[C:6]([O:13][CH3:14])[CH:5]=[CH:4][C:3]=1[C:15](=[O:17])C>C(O)C>[CH:15](=[O:17])[C:3]1[CH:2]=[CH:7][C:6]([O:13][CH3:14])=[CH:5][CH:4]=1

参加物

3

反応物 1

HCID 14078470HCID 14078470、化合物

生成物 1

HCID 312444-Methoxybenzaldehyde

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

In 5 ml of ethanol were dissolved 0.48 g of 2'-hydroxy-4'-methoxy-3'-(3-methyl-2-butenyl)acetophenone obtained in production Example 9 and 0.35 ml of p-anisaldehyde. The solution was cooled to 0° C. and 7.5 ml of a saturated ethanol solution of potassium hydroxide was added to the solution, and the mixture was stirred at 0° C for 30 minutes and at room temperature for 4 days. After the reaction, 3N hydrochloric acid was added to the reaction liquid under cooling to gradually make the liquid acidic, and the formed precipitate was recovered by filtration and recrystallized from methanol to obtain 0.47 g (yield=64.7%) of 2'-hydroxy-4,4'-dimethoxy-3'-(3-methyl-2-butenyl)chalcone in the form of a yellow needle.

出典と根拠

ORDレコード
ord-49ce5b3fc9b541c1a0cbdb372179414d
出典データセット
uspto-grants-1992_04
特許番号
US05106871

反応ノート

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