関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Durene | HCID 7269 | — |
| 反応物 | 1-(5-Bromo-6-methoxynaphthalen-2-yl)ethan-1-one | HCID 622178 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 2-Acetyl-6-methoxynaphthalene | HCID 77506 | — |
反応手順
30 Grams of anhydrous aluminum chloride are added portionwise to a mixture made of 41.85 g of 2-acetyl-5-bromo-6-methoxynaphthalene, 22.15 g of durene and 180 ml of anhydrous methylene chloride cooled to -5° C., in such a manner that the temperature of 20° C. is not exceeded. The reaction mixture is kept for 2 hours at room temperature after the end of the addition and then it is worked as in example 1 obtaining 27.1 g of product with a yield equal to 90.6% calculated on the basis of the starting material 2-acetyl-5-bromo-6-methoxynaphthalene.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US05107013 |
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| 出典データセット | uspto-grants-1992_04 |
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| ORD ID | ord-b4a10eb295bd4f019ba365ffbfd34a06 |
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| 出典メモ | uspto-grants-1992_04 |
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