Carbonate Ion → 3,7-Diethyl-1-(6-hydroxy-6-methylheptyl)-xanthine

HRID 1031076ノート

反応式

HRID 1031076 の反応式
[CH2:1]([N:3]1[C:11]2[N:10]=[CH:9][N:8]([CH2:12][CH3:13])[C:7]=2[C:6](=[O:14])[NH:5][C:4]1=[O:15])[CH3:2].C(=O)([O-])[O-].Br[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][C:26]([OH:29])([CH3:28])[CH3:27]>CN(C)C=O>[CH2:1]([N:3]1[C:11]2[N:10]=[CH:9][N:8]([CH2:12][CH3:13])[C:7]=2[C:6](=[O:14])[N:5]([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][C:26]([OH:29])([CH3:28])[CH3:27])[C:4]1=[O:15])[CH3:2]

参加物

5

反応物 3

HCID 19660Carbonate IonHCID 3507183,7-DiethylxanthineHCID 234396987-Bromo-2-methylheptan-2-ol

生成物 1

HCID 98625993,7-Diethyl-1-(6-hydroxy-6-methylheptyl)-xanthine

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

6.2 g of 3,7-diethylxanthine, 4.1 g of ptassium carbonate, and 6.6 g of 1-bromo-6-hydroxy-6-methylheptane are stirred in 100 ml of dimethylformamide at 120° C. for 18 hours. The mixture is filtered hot with suction, the filtrate is concentrated under recuced pressure final recrystallization from diisopropylether with addition of petroleum ether.

後処理

  1. filtrationThe mixture is filtered hot with suction
  2. concentrationthe filtrate is concentrated under recuced pressure final
  3. customrecrystallization from diisopropylether
  4. additionwith addition of petroleum ether

出典と根拠

ORDレコード
ord-99b567231b784caa8db1791373953f7c
出典データセット
uspto-grants-1992_04
特許番号
US05109003

反応ノート

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