Ammonia → N-benzyl-5,6-dihydroxyisoindoline
反応式
Br.[CH2:2]([N:9]1[CH2:17][C:16]2[C:11](=[CH:12][C:13]([OH:19])=[C:14]([OH:18])[CH:15]=2)[CH2:10]1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.N>CO>[CH2:2]([N:9]1[CH2:10][C:11]2[C:16](=[CH:15][C:14]([OH:18])=[C:13]([OH:19])[CH:12]=2)[CH2:17]1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1参加物
4
実験手順
1.0 g (3.1 mmol) of N-benzyl-5,6-dihydroxyisoindoline hydrobromide was dissolved in 40 ml of a 50% methanol aqueous solution, and the solution was adjusted to pH 8.0 with 8% aqueous ammonia. The precipitated crystals were collected by filtration and washed with 5 ml of cold water and 5 ml of cold acetone to obtain 640 mg of the above identified compound.
後処理
- filtrationThe precipitated crystals were collected by filtration
- washwashed with 5 ml of cold water and 5 ml of cold acetone
- customto obtain 640 mg of the
出典と根拠
- ORDレコード
- ord-1edfc9d200314d5dbbbe054d5acaa62a
- 出典データセット
- uspto-grants-1990_09
- 特許番号
- US04958029
反応ノート
読み込み中…