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1-tert-Butoxy-N,N,N',N'-tetrapropylmethanediamine → N,N-dipropyl-N-[2-(7-nitro-1H-indazol-4-yl)ethenyl]amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-tert-Butoxy-N,N,N',N'-tetrapropylmethanediamine | HCID 13771313 | — |
| 反応物 | 4-Methyl-7-nitro-1H-indazole | HCID 22166018 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | N,N-dipropyl-N-[2-(7-nitro-1H-indazol-4-yl)ethenyl]amine | HCID 54102292 | 90.7% |
反応手順
2.1 g of 4-methyl-7-nitro-1H-indazole and 5.0 g of tert-butoxybis(dipropylamino)methane are heated to 80° C. in 10 ml of tetrahydrofuran for 2.5 hours. The mixture is concentrated, distilled with tetrahydrofuran, and recrystallized from dichloromethane/hexane, yielding 3.1 g of N,N-dipropyl-N-[2-(7-nitro-1H-indazol-4-yl)ethenyl]amine, mp 166°-167° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04958026 |
| 出典データセット | uspto-grants-1990_09 |
| ORD ID | ord-76073e69a49c4844a03b0e57a7e14f84 |
| 出典メモ | uspto-grants-1990_09 |