化工社化工社 化学情報印刷レポート · 研究参考用
N,N-dimethyl-N-[2-(7-nitro-1H-indazol-4-yl)ethenyl]amine → 2-(7-nitro-1H-indazol-4-yl)acetonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N,N-dimethyl-N-[2-(7-nitro-1H-indazol-4-yl)ethenyl]amine | HCID 54098844 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-(7-nitro-1H-indazol-4-yl)acetonitrile | HCID 13629308 | 78.9% |
反応手順
At room temperature, 23.3 g of N,N-dimethyl-N-[2-(7-nitro-1H-indazol-4-yl)ethenyl]amine and 35.0 g of hydroxylamine-orthosulfonic acid are agitated in 400 ml of water for 24 hours. The precipitate is suctioned off, washed with water, and recrystallized from ethyl acetate, thus obtaining 16.0 g of 2-(7-nitro-1H-indazol-4-yl)acetonitrile, mp 198°-200° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04958026 |
| 出典データセット | uspto-grants-1990_09 |
| ORD ID | ord-a29ec0adc9fb4b87a8123b7be4c25b04 |
| 出典メモ | uspto-grants-1990_09 |