Methyl 3-(2-furyl)propanoate → 3-(furan-2-yl)-N-methylpropanamide

反応式

[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][CH2:7][C:8]([O:10]C)=O.CO.[CH3:14][NH2:15]>>[CH3:14][NH:15][C:8](=[O:10])[CH2:7][CH2:6][C:2]1[O:1][CH:5]=[CH:4][CH:3]=1

参加物

反応物 2

HCID 263167Methyl 3-(2-furyl)propanoate

HCID 57454252Monomethylamine methanol

生成物 1

HCID 190863173-(furan-2-yl)-N-methylpropanamide

実験手順

A solution of methyl 3-(furan-2-yl)propanate (4.0 g) in 40% methylamine methanol solution (50 ml) was stirred for 5 hours at room temperature. The solvent was removed under reduced pressure to afford N-methyl-3-(furan-2-yl)propanamide (4.0 g).

後処理

customThe solvent was removed under reduced pressure

出典と根拠

ORDレコード: ord-51ccb07d8b1d453ca6119ee7048fb737
出典データセット: uspto-grants-1994_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05308857

反応ノート

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