反応式
C([NH:4][CH2:5][C:6]1[O:10][C:9]([C:11]2[N:12]=[C:13]([N:16]=[C:17]([NH2:19])[NH2:18])[S:14][CH:15]=2)=[CH:8][CH:7]=1)(=O)C.Cl.C(=O)([O-])[O-].[K+].[K+]>>[NH2:4][CH2:5][C:6]1[O:10][C:9]([C:11]2[N:12]=[C:13]([N:16]=[C:17]([NH2:19])[NH2:18])[S:14][CH:15]=2)=[CH:8][CH:7]=1参加物
4
実験手順
A solution of 4-(5-acetylaminomethylfuran-2-yl)-2-(diaminomethyleneamino)thiazole (4.76 g) in 1N-hydrochloric acid (51.1 ml) was refluxed for 8 hours with stirring. The solution was made basic to pH 10 with an aqueous potassium carbonate. The resulting precipitate was collected by filtration and washed with water to afford 4-(5-aminomethylfuran-2-yl)-2-(diaminomethyleneamino)thiazole (4.03 g).
後処理
- filtrationThe resulting precipitate was collected by filtration
- washwashed with water
出典と根拠
- ORDレコード
- ord-7401d3bde3de47acabaa59149a105009
- 出典データセット
- uspto-grants-1994_05
- 特許番号
- US05308857
関連ノート
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