Dimethylformamide → 2-Hydroxy-6-octyloxycarbonylnaphthalene

HRID 1033146

反応式

HRID 1033146 の反応式
F[C:2](F)(F)[CH:3]([OH:10])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].CN(C)[CH:15]=[O:16].[CH2:18](N(CC)CC)[CH3:19].[C:25]1([C:34]2[CH:39]=[CH:38][C:37]([C:40](Cl)=[O:41])=CC=2)[CH:30]=[CH:29]C(C(Cl)=O)=CC=1>C(Cl)Cl>[OH:10][C:3]1[CH:4]=[CH:5][C:6]2[C:18](=[CH:19][CH:9]=[C:8]([C:15]([O:41][CH2:40][CH2:37][CH2:38][CH2:39][CH2:34][CH2:25][CH2:30][CH3:29])=[O:16])[CH:7]=2)[CH:2]=1

参加物

6

反応物 4

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 75374[1,1'-Biphenyl]-4,4'-dicarbonyl dichlorideHCID 978042-Octanol, 1,1,1-trifluoro-

生成物 1

HCID 542866972-Hydroxy-6-octyloxycarbonylnaphthalene収率 105.5%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

Optically active 1,1,1-trifluoro-2-octanol (0.5 g), dimethylformamide (0.35 g) and triethylamine (0.64 g) were dissolved in 20 ml of methylene chloride. To this solution was added in small portions a solution of 4,4'-biphenyldicarboxylic acid dichloride (1.6 g) obtained in 2) of Example 7 in 50 ml of methylene chloride under ice-cooling, and the mixture was stirred for about 20 hours. Next, 2-hydroxy-6-octyloxycarbonylnaphthalene (0.86 g) obtained in 1) was dissolved in 30 ml of methylene chloride and added in small portions to the reaction mixture. The resulting mixture was stirred for about 20 hours.

後処理

  1. temperaturecooling

出典と根拠

ORDレコード
ord-637059eaa21948d0bda6664d9a4400bd
出典データセット
uspto-grants-1994_05
特許番号
US05310500

関連ノート

読み込み中…