1-Chloro-4-(4-nitrophenoxy)benzene → 4-(4-Chlorophenoxy)aniline

HRID 1033762

反応式

HRID 1033762 の反応式
[Cl:1][C:2]1[CH:17]=[CH:16][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([N+:13]([O-])=O)=[CH:9][CH:8]=2)=[CH:4][CH:3]=1.[H][H]>C(O)C.[Pt]=O>[Cl:1][C:2]1[CH:17]=[CH:16][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([NH2:13])=[CH:9][CH:8]=2)=[CH:4][CH:3]=1

参加物

5

反応物 2

HCID 157861-Chloro-4-(4-nitrophenoxy)benzeneHCID 178418361HCID 178418361、化合物

生成物 1

HCID 75784-(4-Chlorophenoxy)aniline収率 99.3%

試薬・触媒・溶媒 2

HCID 82844Platinum oxide (PtO)触媒HCID 702Ethanol溶媒

実験手順

A suspension of 16.0 g (64.1 mmole) of 4-(4'-chlorophenoxy) nitrobenzene and 75% Pt, 161 mg of platinum oxide (641 μmole, 1 mole %) in 200 ml of ethanol was stirred vigorously under hydrogen until hydrogen uptake ceased (about 4 hours). The suspension was filtered through celite and the solution was evaporated to dryness to obtain 13.94 g (99.3%) of the desired product as a pale brown solid.

後処理

  1. custom(about 4 hours)
  2. filtrationThe suspension was filtered through celite
  3. customthe solution was evaporated to dryness

出典と根拠

ORDレコード
ord-9d73f6d5019449579646c420f3cb77bc
出典データセット
uspto-grants-1994_05
特許番号
US05312830

関連ノート

読み込み中…