Cyclohexene → Diethyl 2-hydroxyethoxymethanephosphonate
反応式
C([O:8][CH2:9][CH2:10][O:11][CH2:12][P:13](=[O:20])([O:17][CH2:18][CH3:19])[O:14][CH2:15][CH3:16])C1C=CC=CC=1.C1CCCCC=1>C(O)C>[OH:8][CH2:9][CH2:10][O:11][CH2:12][P:13](=[O:20])([O:14][CH2:15][CH3:16])[O:17][CH2:18][CH3:19]参加物
4
実験手順
Paladium on carbon (10%, 100 mg) was added to a solution of diethyl 2-(benzyloxy)ethoxymethylphosphonate prepared in accordance with the process of Example II above (0.9 g,2.8 mmol) and cyclohexene (2.0 ml,20 mmol) in 20 ml ethanol under a nitrogen atmosphere. The resulting slurry was heated to reflux overnight. The catalyst was filtered off and the solution concentrated under vacuum to yield 0.5 g of diethyl 2-hydroxyethoxymethylphosphonate.
後処理
- temperatureThe resulting slurry was heated
- temperatureto reflux overnight
- filtrationThe catalyst was filtered off
- concentrationthe solution concentrated under vacuum
出典と根拠
- ORDレコード
- ord-43627a0b5bad4f6dbca379d9cde5dbe7
- 出典データセット
- uspto-grants-1994_05
- 特許番号
- US05312953
反応ノート
読み込み中…