HCID 178447443、化合物 → HCID 178447440、化合物
反応式
C([C@H]1CC[C@H](OC2C=C3C(=CC=2)C=C(C([N+]([O-])=O)(C)CCC(O)=O)C=C3)CC1)(C)(C)C.[C:32]([C@H:36]1[CH2:41][CH2:40][C@H:39]([O:42][C:43]2[C:44]([C:64]([F:67])([F:66])[F:65])=[C:45]3[C:50](=[CH:51][CH:52]=2)[CH:49]=[C:48]([C:53]([N+:61]([O-:63])=[O:62])([CH3:60])[CH2:54][CH2:55][C:56]([O:58]C)=[O:57])[CH:47]=[CH:46]3)[CH2:38][CH2:37]1)([CH3:35])([CH3:34])[CH3:33]>>[C:32]([C@H:36]1[CH2:37][CH2:38][C@H:39]([O:42][C:43]2[C:44]([C:64]([F:65])([F:66])[F:67])=[C:45]3[C:50](=[CH:51][CH:52]=2)[CH:49]=[C:48]([C:53]([N+:61]([O-:63])=[O:62])([CH3:60])[CH2:54][CH2:55][C:56]([OH:58])=[O:57])[CH:47]=[CH:46]3)[CH2:40][CH2:41]1)([CH3:33])([CH3:34])[CH3:35]参加物
3
実験手順
4-(6-(trans-4-tert-butylcyclohexyloxy)-5-(trifluoromethyl)naphthalen-2-yl)-4-nitropentanoic acid was synthesized as per 4-(6-(trans-4-tert-butylcyclohexyloxy)naphthalen-2-yl)-4-nitropentanoic acid (Example 206) in 10% yield using methyl 4-(6-(trans-4-tert-butylcyclohexyloxy)-5-(trifluoromethyl)naphthalen-2-yl)-4-nitropentanoate as starting material.
出典と根拠
- ORDレコード
- ord-4463a25ff0b143a99d408f7b8bd5cda3
- 出典データセット
- uspto-grants-2013_10