Ethyl 4,5-dibromothiophene-2-carboxylate → Ethyl 4-bromo-5-(3-chlorophenyl)thiophene-2-carboxylate
反応式
[Br:1][C:2]1[CH:3]=[C:4]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[S:5][C:6]=1[C:7]1[CH:12]=[C:11](F)[CH:10]=[C:9]([Cl:14])[CH:8]=1.BrC1C=C(C(OCC)=O)SC=1Br>>[Br:1][C:2]1[CH:3]=[C:4]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[S:5][C:6]=1[C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([Cl:14])[CH:8]=1参加物
3
実験手順
The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 9A starting with the compound from Example 8A. 125 mg (57% of theory) of the title compound are obtained.
出典と根拠
- ORDレコード
- ord-7f1c8a2e60684095a4b6c4cb14060a1f
- 出典データセット
- uspto-grants-2013_10
- 特許番号
- US08546438B2
反応ノート
読み込み中…