2-Bromoethyl methyl ether → 3-(2-methoxyethyl)-5-methyl-4-phenyl-3H-thiazol-2-ylideneamine hydrobromide

反応式

[CH3:1][C:2]1[S:6][C:5]([NH2:7])=[N:4][C:3]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[CH3:14][O:15][CH2:16][CH2:17][Br:18]>>[BrH:18].[CH3:14][O:15][CH2:16][CH2:17][N:4]1[C:3]([C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)=[C:2]([CH3:1])[S:6][C:5]1=[NH:7]

参加物

反応物 2

HCID 809722-Bromoethyl methyl ether

HCID 961292-Amino-4-phenyl-5-methylthiazole

生成物 1

HCID 686222923-(2-methoxyethyl)-5-methyl-4-phenyl-3H-thiazol-2-ylideneamine hydrobromide

実験手順

A mixture of 5-methyl-4-phenyl-thiazol-2-ylamine (300 mg, 1.58 mmol) and 2-bromoethyl methyl ether (300 μL, 3.20 mmol) was processed using the method described in Example 12A to provide the title compound.

出典と根拠

ORDレコード: ord-a3f76e6ea72e43449cd8f4d7faf8775d
出典データセット: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08546583B2

反応ノート

読み込み中…