1,3-Dichloro-2-isocyanatobenzene → 1-[6-(3-Chloro-phenylamino)-pyrimidin-4-yl]-3-(2,6-dichloro-Phenyl)-urea

反応式

[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[CH:14]=[C:13]([NH2:15])[N:12]=[CH:11][N:10]=2)[CH:5]=[CH:6][CH:7]=1.[Cl:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([Cl:23])[C:18]=1[N:24]=[C:25]=[O:26]>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]2[N:10]=[CH:11][N:12]=[C:13]([NH:15][C:25]([NH:24][C:18]3[C:19]([Cl:23])=[CH:20][CH:21]=[CH:22][C:17]=3[Cl:16])=[O:26])[CH:14]=2)[CH:5]=[CH:6][CH:7]=1

参加物

反応物 2

HCID 6045371,3-Dichloro-2-isocyanatobenzene

HCID 66669982N~4~-(3-chlorophenyl)pyrimidine-4,6-diamine

生成物 1

HCID 577102231-[6-(3-Chloro-phenylamino)-pyrimidin-4-yl]-3-(2,6-dichloro-Phenyl)-urea

実験手順

The title compound is prepared analogously as described in Example 127 from N-(3-chloro-phenyl)-pyrimidine-4,6-diamine and 2,6-dichlorophenyl isocyanate.

出典と根拠

ORDレコード: ord-f8c066d400814211b9abf2786bf6c32f
出典データセット: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08552002B2

反応ノート

読み込み中…