Acetic Anhydride → HCID 58938508、化合物
反応式
[NH2:1][C:2]1[C:7]([C:8]([NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:9])=[CH:6][N:5]=[CH:4][N:3]=1.[C:17](OC(=O)C)(=O)[CH3:18]>>[CH3:17][C:18]1[N:10]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:8](=[O:9])[C:7]2[C:2]([N:1]=1)=[N:3][CH:4]=[N:5][CH:6]=2参加物
3
反応条件
- 温度
- 120 °C
実験手順
Compound 23 (70.0 mg, 0.32 mmol) was mixed with 6 mL of acetic anhydride and the reaction mixture was stirred at 120° C. for 2 h while monitored by MS. The reaction mixture was then concentrated in vacuo to yield 75 mg of crude compound 24 which was used for the next step without further purification.
後処理
- concentrationThe reaction mixture was then concentrated in vacuo
出典と根拠
- ORDレコード
- ord-4f9edf472b2749fd9f2e4ed09783173b
- 出典データセット
- uspto-grants-2013_10
- 特許番号
- US08552009B2
反応ノート
読み込み中…