Ethyl Acetate → HCID 55281286、化合物

HRID 1039121

反応式

HRID 1039121 の反応式
[NH:1]([C:3](=[S:6])OC)[NH2:2].[NH:7]1[CH2:12][CH2:11][CH:10]([OH:13])[CH2:9][CH2:8]1.C(OCC)(=O)C>C(O)C>[NH:1]([C:3]([N:7]1[CH2:12][CH2:11][CH:10]([OH:13])[CH2:9][CH2:8]1)=[S:6])[NH2:2]

参加物

5

反応物 3

HCID 8857Ethyl AcetateHCID 79341Piperidin-4-olHCID 10171237O-methyl hydrazinecarbothioate

生成物 1

HCID 55281286HCID 55281286、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

反応条件

温度
90 °C

実験手順

A solution of methyl hydrazinecarbothioate (1.0 g, 8.2 mmol) and piperidin-4-ol (1.24 g, 12.3 mmol) in ethanol (7 mL) was refluxed with heating at 90° C. for 2 days. After addition of ethyl acetate, the reaction solution was washed with saturated aqueous sodium chloride, dried over anhydrous magnesium sulfate and concentrated to give the crude desired product. The crude product was used directly for the next reaction.

後処理

  1. washthe reaction solution was washed with saturated aqueous sodium chloride
  2. dry with materialdried over anhydrous magnesium sulfate
  3. concentrationconcentrated

出典と根拠

ORDレコード
ord-ffdf41338bfb4baf90c4987ed35a4d2c
出典データセット
uspto-grants-2013_10
特許番号
US08552031B2

関連ノート

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