Hydroxylamine → Methyl 4-[(hydroxyimino)methyl]-1-naphthalenecarboxylate
反応式
[CH:1]([C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([C:13]([O:15][CH3:16])=[O:14])=[CH:5][CH:4]=1)=O.[NH2:17][OH:18]>CO>[OH:18][N:17]=[CH:1][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([C:13]([O:15][CH3:16])=[O:14])=[CH:5][CH:4]=1参加物
4
実験手順
To a stirred solution of methyl 4-formyl-1-naphthalenecarboxylate (2.2 g, 10.3 mmol) in methanol (50 mL) was added a solution of hydroxylamine (1.33 mL, 50% in water). After stirring at room temperature for 2 h, the reaction mixture was concentrated under reduced pressure to provide the title compound as a pale yellow solid (2.55 g).
後処理
- concentrationthe reaction mixture was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-3f63e521bf104c9ea6defd3616f2ce69
- 出典データセット
- uspto-grants-2013_10
- 特許番号
- US08552218B2
反応ノート
読み込み中…