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1,2-Dichloroethane → 6-Amino-2-[bis(carboxymethyl)amino]hexanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,2-Dichloroethane | HCID 11 | — |
| 反応物 | N-(5-Amino-1-carboxypentyl)iminodiacetic acid | HCID 7019830 | — |
| 溶媒 | Dimethyl Sulfoxide | HCID 679 | — |
| 生成物 | 6-Amino-2-[bis(carboxymethyl)amino]hexanoic acid | HCID 2735296 | — |
反応手順
A solution was prepared by the addition of 1 mmol of EDC and 0.2 mmol of NHS to 1 ml of DMSO, and 50 μl of the thus prepared solution was added onto the CMD film. The solution was then allowed to undergo the reaction at the room temperature for 30 minutes. After the solution was removed, washing with DMSO was performed one time. Also, a solution prepared by the addition of 0.1 mmol of AB-NTA (supplied by Dojin Kagaku K.K.) to 1 ml of DMSO was allowed to undergo the reaction for 12 hours. The solution was removed, and washing with ultra pure water was performed one time.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08557194B2 |
| 出典データセット | uspto-grants-2013_10 |
| ORD ID | ord-875e695d231845f9836da25fe77b3704 |
| 出典メモ | uspto-grants-2013_10 |