1,2-Dichloroethane → 6-Amino-2-[bis(carboxymethyl)amino]hexanoic acid

HRID 1041821

反応式

HRID 1041821 の反応式
C(Cl)CCl.[CH2:5]([CH2:9][C@H:10]([N:14]([CH2:19][C:20]([OH:22])=[O:21])[CH2:15][C:16]([OH:18])=[O:17])[C:11]([OH:13])=[O:12])[CH2:6][CH2:7][NH2:8]>CS(C)=O>[NH2:8][CH2:7][CH2:6][CH2:5][CH2:9][CH:10]([N:14]([CH2:19][C:20]([OH:22])=[O:21])[CH2:15][C:16]([OH:18])=[O:17])[C:11]([OH:13])=[O:12]

参加物

4

反応物 2

HCID 111,2-DichloroethaneHCID 7019830N-(5-Amino-1-carboxypentyl)iminodiacetic acid

生成物 1

HCID 27352966-Amino-2-[bis(carboxymethyl)amino]hexanoic acid

試薬・触媒・溶媒 1

HCID 679Dimethyl Sulfoxide溶媒2 回

実験手順

A solution was prepared by the addition of 1 mmol of EDC and 0.2 mmol of NHS to 1 ml of DMSO, and 50 μl of the thus prepared solution was added onto the CMD film. The solution was then allowed to undergo the reaction at the room temperature for 30 minutes. After the solution was removed, washing with DMSO was performed one time. Also, a solution prepared by the addition of 0.1 mmol of AB-NTA (supplied by Dojin Kagaku K.K.) to 1 ml of DMSO was allowed to undergo the reaction for 12 hours. The solution was removed, and washing with ultra pure water was performed one time.

後処理

  1. additionwas added onto the CMD film
  2. customthe reaction at the room temperature for 30 minutes
  3. customAfter the solution was removed
  4. washwashing with DMSO
  5. customthe reaction for 12 hours
  6. customThe solution was removed
  7. washwashing with ultra pure water

出典と根拠

ORDレコード
ord-875e695d231845f9836da25fe77b3704
出典データセット
uspto-grants-2013_10
特許番号
US08557194B2

関連ノート

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