化工社化工社 化学情報印刷レポート · 研究参考用
Cyanuric chloride → Tert-butyl ((2r,5s,7as)-5-cyano-3-oxohexahydropyrrolizin-2-yl)carbamate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyanuric chloride | HCID 7954 | — |
| 反応物 | Tert-butyl ((2r,5s,7as)-5-carbamoyl-3-oxohexahydropyrrolizin-2-yl)carbamate | HCID 90895673 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | Tert-butyl ((2r,5s,7as)-5-cyano-3-oxohexahydropyrrolizin-2-yl)carbamate | HCID 91321587 | — |
反応手順
100 mg of tert-butyl ((2R,5S,7aS)-5-carbamoyl-3-oxohexahydropyrrolizin-2-yl)carbamate were dissolved in 2 ml of dimethylformamide, and 65 mg of cyanuric chloride were added. The mixture was stirred for 3 h, and the dimethylformamide was removed in vacuo. The residue was chromatographed on silica gel.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07094800B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-93eff2bf0daa450c897e724582f37625 |
| 出典メモ | uspto-grants-2006_08 |