Trifluoromethyl toluidine → HCID 59427843、化合物

反応式

[CH3:1][C:2]1[C:8]([C:9]([F:12])([F:11])[F:10])=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].[Cl:13][C:14]1[CH:22]=[CH:21][C:17]([C:18](Cl)=[O:19])=[CH:16][C:15]=1[I:23]>>[Cl:13][C:14]1[CH:22]=[CH:21][C:17]([C:18]([NH:4][C:3]2[CH:5]=[CH:6][CH:7]=[C:8]([C:9]([F:10])([F:11])[F:12])[C:2]=2[CH3:1])=[O:19])=[CH:16][C:15]=1[I:23]

参加物

反応物 2

HCID 2735932Trifluoromethyl toluidine

HCID 573499404-Chloro-3-iodobenzoyl chloride

生成物 1

HCID 59427843HCID 59427843、化合物

実験手順

4-Chloro-3-iodo-N-(2-methyl-3-(trifluoromethyl)phenyl)benzamide was synthesized from 2-methyl-3-(trifluromethyl)aniline and 4-chloro-3-iodobenzoyl chloride according to the procedure described in Example 183. 4-Chloro-3-iodo-N-(2-methyl-3-(trifluoromethyl)phenyl)benzamide was obtained as a white solid. MS (M−H+) 437.8; Calculated for C15H10ClF3INO: 439.

出典と根拠

ORDレコード: ord-508f26560ae849b39da487fe1f9a8412
出典データセット: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08557996B2

反応ノート

読み込み中…

参加物