Nitrogen → 5-Nitro-2-pentanone

HRID 1044731ノート

反応式

HRID 1044731 の反応式
N#N.[CH:3]([C:5]([CH3:7])=[O:6])=[CH2:4].[N+:8]([CH3:11])([O-:10])=[O:9]>>[N+:8]([CH2:11][CH2:4][CH2:3][C:5](=[O:6])[CH3:7])([O-:10])=[O:9]

参加物

4

反応物 3

HCID 947NitrogenHCID 6375NitromethaneHCID 6570Methyl vinyl ketone

生成物 1

HCID 42950035-Nitro-2-pentanone

実験手順

In a flame dried round-bottomed flask equipped with a magnetic stir bar and under inert atmosphere (N2), to a solution of methyl vinyl ketone (2.32 mL, 28.53 mmol) in nitromethane (29.6 mL) was added activated KF/Al2O3 (323 mg, prepared by mixing KF and basic Al2O3 in water followed by concentrating and drying) at 0° C. The reaction mixture was then allowed to warm up to rt and stirred at this temperature for 18 h. The mixture was filtered through neutral Al2O3 and washed with CH2Cl2. The filtrated was concentrated under reduced pressure to give the title compound as a colorless oil.

後処理

  1. additionwas added
  2. customat 0° C
  3. filtrationThe mixture was filtered through neutral Al2O3
  4. washwashed with CH2Cl2
  5. concentrationThe filtrated was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-0d2573c018274854b4e6e64fdc1082d6
出典データセット
uspto-grants-2013_10
特許番号
US08563714B2

反応ノート

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