Phenylmethyl 4-{2-[6-amino-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-9-yl]ethyl}-1-piperidinecarboxylate → 2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[2-(4-piperidinyl)ethyl]-9H-purin-6-amine
反応式
C(OC1N=C2C(N=C(OC)N2CCCC2CCCCN2)=C(N)N=1)CCC.[NH2:27][C:28]1[N:36]=[C:35]([O:37][C@@H:38]([CH3:42])[CH2:39][CH2:40][CH3:41])[N:34]=[C:33]2[C:29]=1[N:30]=[C:31]([O:61][CH3:62])[N:32]2[CH2:43][CH2:44][CH:45]1[CH2:50][CH2:49][N:48](C(OCC2C=CC=CC=2)=O)[CH2:47][CH2:46]1>>[CH3:42][C@H:38]([O:37][C:35]1[N:34]=[C:33]2[C:29]([N:30]=[C:31]([O:61][CH3:62])[N:32]2[CH2:43][CH2:44][CH:45]2[CH2:46][CH2:47][NH:48][CH2:49][CH2:50]2)=[C:28]([NH2:27])[N:36]=1)[CH2:39][CH2:40][CH3:41]参加物
3
反応物 2
生成物 1
実験手順
Prepared similarly to Intermediate 32 from phenylmethyl 4-{2-[6-amino-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-9-yl]ethyl}-1-piperidinecarboxylate.
出典と根拠
- ORDレコード
- ord-5ee866c33f6d49d4bf2e1e7e8b559f03