3'-Methylcinnamanilide → 7-Methyl-2-quinolone

HRID 1045354

反応式

HRID 1045354 の反応式
[C:1]1([CH3:18])[CH:6]=[CH:5][CH:4]=[C:3]([NH:7][C:8](=[O:17])[CH:9]=[CH:10]C2C=CC=CC=2)[CH:2]=1.[Al+3].[Cl-].[Cl-].[Cl-]>O>[CH3:18][C:1]1[CH:2]=[C:3]2[C:4]([CH:10]=[CH:9][C:8](=[O:17])[NH:7]2)=[CH:5][CH:6]=1

参加物

4

反応物 2

HCID 5830183'-MethylcinnamanilideHCID 6451240Aluminum(III) Chloride

生成物 1

HCID 776737-Methyl-2-quinolone収率 903.9%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

N-m-tolylcinnamamide (2 g, 0.834 mmol) and AlCl3 (1.12 g, 0.834 mmol) were heated for 1 h at 100° C. Water was added and the solid was filtered to provide 1.2 g of crude product.

後処理

  1. filtrationthe solid was filtered

出典と根拠

ORDレコード
ord-7f1b868a4e934450bb52fa07c8592317
出典データセット
uspto-grants-2013_10
特許番号
US08569282B2

関連ノート

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