1-benzyl-2-methyl bromo-5-(2,4-difluorophenyl)-1H-imidazole → 1-Benzyl-2-methyl-4-(3-(N-[3-methylbut-2-yl]-N-[cyano]amino)-4-nitrophenyl)-5-(2,4-difluorophenyl)-1H-imidazole

反応式

[C:23](#[N:24])[N:25]([c:26]1[c:27]([N+:40](=[O:41])[O-:42])[cH:28][cH:29][c:30]([B:32]2[O:33][CH2:34][C:35]([CH3:36])([CH3:37])[CH2:38][O:39]2)[cH:31]1)[CH:43]([CH3:44])[CH:45]([CH3:46])[CH3:47].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([CH3:22])[n:10][c:11]([Br:21])[c:12]1-[c:13]1[c:14]([F:20])[cH:15][c:16]([F:19])[cH:17][cH:18]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([CH3:22])[n:10][c:11](-[c:30]2[cH:29][cH:28][c:27]([N+:40](=[O:41])[O-:42])[c:26]([N:25]([C:23]#[N:24])[CH:43]([CH3:44])[CH:45]([CH3:46])[CH3:47])[cH:31]2)[c:12]1-[c:13]1[c:14]([F:20])[cH:15][c:16]([F:19])[cH:17][cH:18]1

参加物

反応物 2

HCID 179816721-benzyl-2-methyl bromo-5-(2,4-difluorophenyl)-1H-imidazole

HCID 86623269N-[cyano]N-[3-methylbut-2-yl]2-nitro-5-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)aniline

生成物 1

HCID 866232681-Benzyl-2-methyl-4-(3-(N-[3-methylbut-2-yl]-N-[cyano]amino)-4-nitrophenyl)-5-(2,4-difluorophenyl)-1H-imidazole

出典と根拠

ORDレコード: ord-eb7e89d13eb547b8972d98ac19b63f18
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…