Methyl 3-chloro-2-oxopropanoate → 2-(7-Nitro-1H-indol-2-yl)-thiazole-4-carboxylic acid methyl ester
反応式
[CH3:1][O:2][C:3](=[O:8])[C:4](=O)[CH2:5]Cl.[N+:9]([C:12]1[CH:13]=[CH:14][CH:15]=[C:16]2[C:20]=1[NH:19][C:18]([C:21](=[S:23])[NH2:22])=[CH:17]2)([O-:11])=[O:10]>>[CH3:1][O:2][C:3]([C:4]1[N:22]=[C:21]([C:18]2[NH:19][C:20]3[C:16]([CH:17]=2)=[CH:15][CH:14]=[CH:13][C:12]=3[N+:9]([O-:11])=[O:10])[S:23][CH:5]=1)=[O:8]参加物
3
実験手順
3-Chloro-2-oxo-propionic acid methyl ester and 7-nitro-1H-indole-2-carbothioic acid amide prepared in Step A of Preparation 110 were reacted according to the same procedure as Preparation 110 to give the title compound.
後処理
- customwere reacted
- customaccording to the same procedure as Preparation 110
出典と根拠
- ORDレコード
- ord-e5b63f360e7a4bf096747d2247f42503
- 出典データセット
- uspto-grants-2013_10
- 特許番号
- US08569307B2
反応ノート
読み込み中…