関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Ethyl cyanoacetate | HCID 7764 | — |
| 反応物 | Triethylorthoaceate | HCID 21875354 | — |
| 生成物 | Ethyl 2-cyano-3-ethoxy-2-butenoate | HCID 46635 | — |
反応手順
A mixture of ethyl 2-cyanoacetate (120 g, 1.06 mol) and triethylorthoacetate (354 g, 2.12 mol) in glacial acetic acid (33 g, 0.53 mol) was stirred at 120-130° C. overnight. The mixture was concentrated under vacuum to provide crude ethyl 2-cyano-3-ethoxybut-2-enoate. The residue was carried into the next reaction without further purification assuming 100% conversion.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08569319B2 |
|---|
| 出典データセット | uspto-grants-2013_10 |
|---|
| ORD ID | ord-90f1f1cbda74454492aa043b75d3489e |
|---|
| 出典メモ | uspto-grants-2013_10 |
|---|
