関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethyl 2-cyano-3-ethoxy-2-butenoate | HCID 46635 | — |
| 反応物 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 生成物 | Ethyl 2-cyano-5-(dimethylamino)-3-ethoxypenta-2,4-dienoate | HCID 54113151 | — |
反応手順
A mixture of ethyl 2-cyano-3-ethoxybut-2-enoate (194 g theory, 1.06 mol) and N,N-dimethylformamide dimethyl acetal (160 g, 1.325 mol) was stirred at 70° C. for 2 hours. The mixture was concentrated under high vacuum to provide crude ethyl 2-cyano-5-(dimethylamino)-3-ethoxypenta-2,4-dienoate. The residue was used directly without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08569319B2 |
|---|
| 出典データセット | uspto-grants-2013_10 |
|---|
| ORD ID | ord-42b4674ae4bd4d4491db943b6f21a621 |
|---|
| 出典メモ | uspto-grants-2013_10 |
|---|
