化工社化工社 化学情報印刷レポート · 研究参考用
Ethanol → Lamivudine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | Lamivudine oxalate | HCID 86677229 | — |
| 溶媒 | Triethylamine | HCID 8471 | — |
| 生成物 | Lamivudine | HCID 60825 | — |
反応手順
Specifically, Lamivudine oxalate is added to ethanol, and an amount of triethylamine is added thereto at the temperature of 40˜45° C. for 0.5 hr, and stirred for 4 h at the same temperature. The mixture is centrifuged at room temperature, and a product is dried under vacuum at the temperature of 40˜45° C. to obtain Lamivudine crystal.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08569322B2 |
| 出典データセット | uspto-grants-2013_10 |
| ORD ID | ord-eb7e2ad85efd4d20b3416678baf39123 |
| 出典メモ | uspto-grants-2013_10 |