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HRID 1046041作成日:2026年10月26日

Ethanol → Lamivudine

https://huagongshe.com/reaction/1046041

反応式

関与物質

役割名称HCID仕込み量
反応物EthanolHCID 702—
反応物Lamivudine oxalateHCID 86677229—
溶媒TriethylamineHCID 8471—
生成物LamivudineHCID 60825—

反応手順

To 1000 ml of ethanol was added 120 g of Lamivudine oxalate (prepared by the method of the present invention). 60 ml of triethylamine was added thereto at the temperature of 40˜45° C. for 0.5 hour, and stirred at the same temperature for 4 hours. The mixture was centrifuged at room temperature and dried under vacuum at the temperature of 40˜45° C. to obtain Lamivudine crystal.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08569322B2
出典データセットuspto-grants-2013_10
ORD IDord-68b61474faa448258e96bdf8c60bc55c
出典メモuspto-grants-2013_10