Propranolol Hydrochloride → Propranolol

HRID 10485

反応式

HRID 10485 の反応式
[N-]1C=CCC1=O.[CH3:7][CH:8]([NH:10][CH2:11][CH:12]([OH:25])[CH2:13][O:14][C:15]1[CH:16]=[CH:17][CH:18]=[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=12)[CH3:9].Cl>O>[CH3:9][CH:8]([NH:10][CH2:11][CH:12]([OH:25])[CH2:13][O:14][C:15]1[CH:16]=[CH:17][CH:18]=[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=12)[CH3:7]

参加物

4

実験手順

40.0 g of N-pyrrolidone, 20.0 g of propranolol HCl and 20.0 g of polyvinylpyrrolidone with a K value of 90 are dissolved in 40.0 g of demineralized water. This solution is incorporated into 333.3 g of 30% strength polyvinyl acetate dispersion of the invention while stirring. A 200 μm knife is used to spread this mixture onto a 40 μm-thick polyester sheet, which is then dried at 60° C. The spreading process is repeated once more to increase the layer thickness. After covering the polymer layer with a siliconized released liner it is possible to punch out any desired shapes.

後処理

  1. customis then dried at 60° C
  2. temperatureto increase the layer thickness

出典と根拠

ORDレコード
ord-e3a5ad80c6b74560b8516211a0d54e1d
出典データセット
uspto-grants-2006_08
特許番号
US07094831B2

関連ノート

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