4-Isopropylaniline → 4-bromo-N-(4-isopropylphenyl)picolinamide

反応式

[Br:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]([OH:10])=O)[CH:3]=1.[CH:11]([C:14]1[CH:20]=[CH:19][C:17]([NH2:18])=[CH:16][CH:15]=1)([CH3:13])[CH3:12]>>[Br:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([C:8]([NH:18][C:17]2[CH:19]=[CH:20][C:14]([CH:11]([CH3:13])[CH3:12])=[CH:15][CH:16]=2)=[O:10])[CH:3]=1

参加物

反応物 2

HCID 74644-Isopropylaniline

HCID 7351504-Bromopyridine-2-carboxylic acid

生成物 1

HCID 866958534-bromo-N-(4-isopropylphenyl)picolinamide

実験手順

In a manner similar to that describe in Preparation 34, 4-bromo-pyridine-2-carboxylic acid and 4-isopropylaniline were converted to the title compound.

出典と根拠

ORDレコード: ord-344c7c3f2a3d40f5b8bb5f1b023e74a4
出典データセット: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09388176B2

反応ノート

読み込み中…