Dimethylformamide → 5-fluoro-N-(trans-4-hydroxy-cyclohexyl)-2-(4-methylsulfanyl-phenoxy)-nicotinamide

反応式

[C:28](=[O:29])([O-:30])[O-:31].[CH3:19][S:20][c:21]1[cH:22][cH:23][c:24]([OH:27])[cH:25][cH:26]1.[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][CH:7]2[CH2:8][CH2:9][CH:10]([OH:13])[CH2:11][CH2:12]2)[cH:14][c:15]([F:18])[cH:16][n:17]1.[Cs+:32].[Cs+:33].[O:34]=[CH:35][N:36]([CH3:37])[CH3:38]>>[c:2]1([O:27][c:24]2[cH:23][cH:22][c:21]([S:20][CH3:19])[cH:26][cH:25]2)[c:3]([C:4](=[O:5])[NH:6][CH:7]2[CH2:8][CH2:9][CH:10]([OH:13])[CH2:11][CH2:12]2)[cH:14][c:15]([F:18])[cH:16][n:17]1