Methylhydrazine → 1-Methyl-5-(2-methyl-propenyl)-3-pyrrolidin-1-yl-1H-[1,2,4]triazole

HRID 1054939ノート

反応式

HRID 1054939 の反応式
CS/[C:3](=[N:9]\[C:10](=O)[CH:11]=[C:12]([CH3:14])[CH3:13])/[N:4]1[CH2:8][CH2:7][CH2:6][CH2:5]1.[CH3:16][NH:17][NH2:18]>>[CH3:16][N:17]1[C:10]([CH:11]=[C:12]([CH3:14])[CH3:13])=[N:9][C:3]([N:4]2[CH2:8][CH2:7][CH2:6][CH2:5]2)=[N:18]1

参加物

3

反応物 2

HCID 6061MethylhydrazineHCID 178503950HCID 178503950、化合物

生成物 1

HCID 900178021-Methyl-5-(2-methyl-propenyl)-3-pyrrolidin-1-yl-1H-[1,2,4]triazole収率 106%

実験手順

Was prepared in the same manner as described in General procedure 1d, using 3-Methyl-but-2-enoic acid 1-methylsulfanyl-1-pyrrolidin-1-yl-meth-(Z)-ylideneamide and methylhydrazine as starting materials. Extraction and evaporation of the solvents afforded 1-Methyl-5-(2-methyl-propenyl)-3-pyrrolidin-1-yl-1H-[1,2,4]triazole (261 mg/106%) as yellow oil. MS: m/z=207.1 (M+H+)

後処理

  1. customWas prepared in the same manner
  2. extractionExtraction and evaporation of the solvents

出典と根拠

ORDレコード
ord-93e425c2cb084313ae4cdcc04edd27b3
出典データセット
uspto-grants-2016_07
特許番号
US09394311B2

反応ノート

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