反応式
[Zn:1].II.[Br:4]CCCCCCCCC(OCC)=O.[C:18]([O:28][CH2:29][CH3:30])(=[O:27])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]>CC(N(C)C)=O>[Br:4][Zn:1][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][C:18]([O:28][CH2:29][CH3:30])=[O:27]参加物
6
反応条件
- 温度
- 80 °C
実験手順
In a dry reaction tube under nitrogen were charged zinc dust (3.70 g, 56.6 mmol), iodine (479 mg, 1.89 mmol) and dry DMA (20 mL). The mixture was stirred at room temperature until the color of iodine disappeared. Ethyl 9-bromononanoate was added, and the mixture was stirred at 80° C. for 4 hours and then at room temperature overnight. (Completion of the zinc insertion reaction was checked by GCMS analysis of the hydrolyzed reaction mixture.) The reaction mixture was used without further treatment in the subsequent step. GCMS m/z 186 [M]+ (ethyl nonanoate).
後処理
- customIn a dry reaction tube under nitrogen
- customat room temperature
- customovernight
出典と根拠
- ORDレコード
- ord-0ef785149a124889a3ddb5d4f53c3659
- 出典データセット
- uspto-grants-2016_07
- 特許番号
- US09393315B2
関連ノート
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