Dipropylamine → 3-Oxo-n,n-dipropylbutanamide
反応式
[CH2:1]([NH:4][CH2:5][CH2:6][CH3:7])[CH2:2][CH3:3].[CH2:8]=[C:9]1[O:13][C:11](=[O:12])[CH2:10]1>CO>[O:13]=[C:9]([CH3:8])[CH2:10][C:11]([N:4]([CH2:5][CH2:6][CH3:7])[CH2:1][CH2:2][CH3:3])=[O:12]参加物
4
反応条件
- 温度
- 0 °C
実験手順
A solution of 27.80 g (0.28 mol) N,N-di-n-propylamine was added dropwise to a solution of 20.00 g (0.24) diketene in 100 ml MeOH at 0° C. After stirring for 3 hours at 0° C., no starting material was detected anymore by thin-layer chromatography. The reaction mixture was spun off and the residue was purified by means of column chromatography. 38.05 g of product was obtained as a slightly yellow oil.
後処理
- customthe residue was purified by means of column chromatography
出典と根拠
- ORDレコード
- ord-907516ec60ca4c8080ab426f6dc95afd
- 出典データセット
- uspto-grants-2016_07
- 特許番号
- US09394324B2
反応ノート
読み込み中…