3-Methyl-5-(pentafluorosulfur)benzoic acid → HCID 89699775、化合物

反応式

[CH3:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[N:9]1[C:16]2[N:12]([N:13]=[C:14]([C:17]3[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=3)[CH:15]=2)[CH:11]=[CH:10]1.[CH3:23][C:24]1[CH:25]=[C:26]([CH:30]=[C:31]([S:33]([F:38])([F:37])([F:36])([F:35])[F:34])[CH:32]=1)[C:27](O)=[O:28]>>[CH3:23][C:24]1[CH:25]=[C:26]([CH:30]=[C:31]([S:33]([F:36])([F:34])([F:35])([F:37])[F:38])[CH:32]=1)[C:27]([NH:6][C:5]1[CH:7]=[CH:8][C:2]([CH3:1])=[C:3]([N:9]2[C:16]3[N:12]([N:13]=[C:14]([C:17]4[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=4)[CH:15]=3)[CH:11]=[CH:10]2)[CH:4]=1)=[O:28]

参加物

反応物 2

HCID 665235893-Methyl-5-(pentafluorosulfur)benzoic acid

HCID 897000234-Methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]aniline

生成物 1

HCID 89699775HCID 89699775、化合物

実験手順

Analogously to the process described in Example 26, 80 mg (0.276 mmol) of the compound of Example 6A and 73 mg (0.276 mmol) of the compound of Example 34A gave 101 mg (61% of theory, 90% pure) of the title compound.

出典と根拠

ORDレコード: ord-e1e0f89ddaab4dfeb339b2c733c0971e
出典データセット: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09394309B2

反応ノート

読み込み中…