Methyl Decanoate → Vanillyl decanoate

HRID 1056461

反応式

HRID 1056461 の反応式
[CH3:1][O:2][C:3](=[O:13])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(O)[C:15]1[CH:23]=[CH:22][C:20]([OH:21])=[C:17]([O:18][CH3:19])[CH:16]=1>CC(C)=O>[C:3]([O:2][CH2:1][C:15]1[CH:23]=[CH:22][C:20]([OH:21])=[C:17]([O:18][CH3:19])[CH:16]=1)(=[O:13])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

参加物

4

反応物 2

HCID 8050Methyl DecanoateHCID 62348Vanillyl alcohol

生成物 1

HCID 15979852Vanillyl decanoate収率 73%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

This compound was synthesized by the method described in Kobata et al. (Biosci. Biotechnol. Biochem., 66(2), 319-327, 2002). Decanoic acid methyl ester (2.13 mL, 10.5 mmol), vanillyl alcohol (1.62 g, 10.5 mmol), molecular sheaves 4 Å (10 g), and Novozyme 435 (2.5 g) were added to acetone (50 mL) and stirred for 2 hours at room temperature. The reaction solution was filtered through cellite and the filtrate was concentrated under reduced pressure. The concentrated residue was purified by silica gel chromatography, yielding 2.25 g (7.30 mmol, 73.0 percent) of vanillyl decanoate in the form of a colorless oily substance.

後処理

  1. customThis compound was synthesized by the method
  2. filtrationThe reaction solution was filtered through cellite
  3. concentrationthe filtrate was concentrated under reduced pressure
  4. customThe concentrated residue was purified by silica gel chromatography

出典と根拠

ORDレコード
ord-11ad05997a0a4c39bef970dce0378f1a
出典データセット
uspto-grants-2016_07
特許番号
US09399030B2

関連ノート

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