化工社化工社 化学情報印刷レポート · 研究参考用
(4-Chlorophenyl)(phenyl)methanamine → (4-Chlorophenyl)(phenyl)methanamine, (S)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (4-Chlorophenyl)(phenyl)methanamine | HCID 409810 | — |
| 反応物 | D-Tartaric acid | HCID 439655 | — |
| 生成物 | (4-Chlorophenyl)(phenyl)methanamine, (S)- | HCID 736032 | — |
反応手順
The racemic 4-chlorobenzhydrylamine was treated with D-tartaric acid, and then sequentially recrystallized ten times from water (as described by Clemo, et al., J. Chem. Soc., (1939), 1958-1960) to provide (S)-4-chlorobenzhydrylamine of high optical purity (ee>98%, according to chiral HPLC).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09399032B2 |
| 出典データセット | uspto-grants-2016_07 |
| ORD ID | ord-5c7d83a10736459f804e1b03d1c4e82d |
| 出典メモ | uspto-grants-2016_07 |