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Hydrochloride methanol → HCID 178418756、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloride methanol | HCID 21893726 | — |
| 反応物 | HCID 178418777 | HCID 178418777 | — |
| 生成物 | HCID 178418756 | HCID 178418756 | — |
反応手順
According to the method of Example 1, Step C, deprotection was performed (room temperature, 2 hours) by using Intermediate 124 (83.9 mg) and 10% hydrogen chloride/methanol solution (2 ml). The solvent was evaporated under reduced pressure, and the residue was added with methanol (0.5 ml) and diethyl ether (1.5 ml). The deposited precipitates were collected by filtration and washed with diethyl ether to obtain the title compound (63.3 mg).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07094789B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-98d12fb782ec41e3aba8ea2af660275d |
| 出典メモ | uspto-grants-2006_08 |