関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Nitric Acid | HCID 944 | — |
| 反応物 | 5-Fluoro-2(3H)-benzoxazolone | HCID 287208 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 5-Fluoro-6-nitro-2,3-dihydro-1,3-benzoxazol-2-one | HCID 11217835 | 88% |
反応手順
In a 500-ml flask, place 100 ml of concentrated nitric acid (70%) and warm to 45° C. Add 30.6 g (0.2 m) of 5-fluoro-benzoxazol-2-one (1a; X=F) and stir at 50° C. for 3 hrs. Add 240 ml of water slowly, and stir and cool to room temperature. Collect solid, wash with water, and dry in air to give 35.0 g (88%) of 5-fluoro-6-nitro-benzoxazol-2-one (2a; X=F) as pale yellow solids.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06515176B1 |
|---|
| 出典データセット | uspto-grants-2003_02 |
|---|
| ORD ID | ord-9a5f5f647d1f4215a437c2010fcf77b0 |
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| 出典メモ | uspto-grants-2003_02 |
|---|
