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Trifluoroacetic acid → 2-[4-(3,4-Dichlorophenoxy)-1-piperidinyl]ethylamine trifluoroacetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trifluoroacetic acid | HCID 6422 | — |
| 反応物 | tert-Butyl 2-[4-(3,4-dichlorophenoxy)-1-piperidinyl]ethylcarbamate | HCID 22322299 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 2-[4-(3,4-Dichlorophenoxy)-1-piperidinyl]ethylamine trifluoroacetate | HCID 22322453 | — |
反応手順
The product from step (iii) was dissolved in dichloromethane (200 ml) and trifluoroacetic acid (100 ml) added. After 18 hrs at room temperature the solvent was evaporated and the resultant gum triturated under ether to give the sub-titled product as a solid (5.7 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06518286B1 |
| 出典データセット | uspto-grants-2003_02 |
| ORD ID | ord-77c8a59065fc41e2ba35816ca6e86ee6 |
| 出典メモ | uspto-grants-2003_02 |