Pyridinium chloride → HCID 178450129、化合物

反応式

[CH3:1][CH:2]([CH3:41])[C:3]([C:29]1[CH:34]=[CH:33][CH:32]=[C:31]([C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][N:36]=2)[CH:30]=1)([C:5]1[N:6]=[CH:7][N:8](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[CH:9]=1)[OH:4].Cl.N1C=CC=CC=1>>[NH:8]1[CH:9]=[C:5]([C:3]([C:29]2[CH:34]=[CH:33][CH:32]=[C:31]([C:35]3[CH:40]=[CH:39][CH:38]=[CH:37][N:36]=3)[CH:30]=2)([OH:4])[CH:2]([CH3:1])[CH3:41])[N:6]=[CH:7]1

参加物

反応物 2

HCID 10176127Pyridinium chloride

HCID 186685632-methyl-1-[3-(2-pyridyl)phenyl]-1-(1-trityl-1H-imidazol-4-yl)-1-propanol

生成物 1

HCID 178450129HCID 178450129、化合物収率 68.3%

実験手順

By the reaction in the same manner as in Example 4-(iii) using 2-methyl-1-[3-(2-pyridyl)phenyl]-1-(1-trityl-1H-imidazol-4-yl)-1-propanol (527 mg), pyridine hydrochloride (205 mg), the title compound (197 mg) was obtained as colorless plate crystals.

後処理

customBy the reaction in the same manner as in Example

出典と根拠

ORDレコード: ord-5bacfe7b3eed43d19bbf2f3b92ea8135
出典データセット: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06518257B1

反応ノート

読み込み中…

参加物