2-Benzyl-5-nitropyridine → 6-Benzylpyridin-3-amine
反応式
[CH2:1]([C:8]1[CH:13]=[CH:12][C:11]([N+:14]([O-])=O)=[CH:10][N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(OCC)(=O)C.[C].[Pd]>[CH2:1]([C:8]1[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][N:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
4
実験手順
389 mg of 2-benzyl-5-nitropyridine was dissolved in ethyl acetate and 153 mg of 10% palladium carbon was added thereto. Then the resulting mixture was stirred under a hydrogen gas stream at room temperature under atmospheric pressure for 30 minutes. Then the reaction mixture was filtered through celite. After distilling off the solvent under reduced pressure, 333 mg of the title compound was obtained as an amber oily substance.
後処理
- filtrationThen the reaction mixture was filtered through celite
- distillationAfter distilling off the solvent under reduced pressure
出典と根拠
- ORDレコード
- ord-3d90a3f3768d4c6cad00aa16c8f3f118
- 出典データセット
- uspto-grants-2003_02
- 特許番号
- US06518423B1
反応ノート
読み込み中…