HCID 54513511、化合物 → 4-Isopropyloxy-2-methylpyridine

HRID 1059869ノート

反応式

HRID 1059869 の反応式
[CH:1]([O:4][C:5]1[CH:10]=[CH:9][N+:8]([O-])=[C:7]([CH3:12])[CH:6]=1)([CH3:3])[CH3:2]>CC(O)C.[Ni]>[CH:1]([O:4][C:5]1[CH:10]=[CH:9][N:8]=[C:7]([CH3:12])[CH:6]=1)([CH3:3])[CH3:2]

参加物

4

反応物 1

HCID 54513511HCID 54513511、化合物

生成物 1

HCID 186675734-Isopropyloxy-2-methylpyridine収率 78.7%

試薬・触媒・溶媒 2

HCID 935Nickel触媒HCID 3776Isopropanol溶媒

実験手順

A suspension of 4-isopropyloxy-2-methylpyridine N-oxide (0.78 g) in 2-propanol (10 ml) was hydrogenated over Raney-nickel (50% suspension in water, 1 ml) under a hydrogen atmosphere for 48 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 4-isopropyloxy-2-methylpyridine (555 mg).

後処理

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-5308d304416e473dab3b9bf7ec755edf
出典データセット
uspto-grants-2003_02
特許番号
US06521643B1

反応ノート

読み込み中…