Benzoic Acid → (2-Amino-5-fluorophenyl)(phenyl)methanone

HRID 1061863ノート

反応式

HRID 1061863 の反応式
[C:1]([OH:9])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:10][C:11]1[CH:17]=[CH:16][C:14]([NH2:15])=[CH:13][CH:12]=1>>[NH2:15][C:14]1[CH:16]=[CH:17][C:11]([F:10])=[CH:12][C:13]=1[C:1]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)=[O:9]

参加物

3

反応物 2

HCID 243Benzoic AcidHCID 97314-Fluoroaniline

生成物 1

HCID 778082(2-Amino-5-fluorophenyl)(phenyl)methanone収率 37.9%

実験手順

The procedure was in the same manner as described in example 15, except that the starting material was benzoic acid instead of p-chlorobenzoic acid and 4-fluoroaniline instead of 4-chloroaniline. The title compound was obtained as yellow needle crystal, and yield 37.9%, m.p. 112-113° C.

出典と根拠

ORDレコード
ord-69ad24d06c9846c4b2f52f293bfab95b
出典データセット
uspto-grants-2005_11
特許番号
US06960611B2

反応ノート

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