5-Amino-2-methylindole → 7-(2-Methyl-1h-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carbonitrile
反応式
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([NH2:11])=[CH:6][CH:5]=2.Cl[C:13]1[CH:18]=[CH:17][N:16]=[C:15]2[CH:19]=[C:20]([C:22]#[N:23])[S:21][C:14]=12>>[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([NH:11][C:13]1[CH:18]=[CH:17][N:16]=[C:15]3[CH:19]=[C:20]([C:22]#[N:23])[S:21][C:14]=13)=[CH:6][CH:5]=2参加物
3
実験手順
The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-chloro-thieno[3,2-b]pyridine-2-carbonitrile by a procedure analogous to Example 1C. MS: 305 (MH+), HPLC Rf: 4.86 min.; HPLC purity: 85%.
出典と根拠
- ORDレコード
- ord-ea492e3343604397b8c24af2ed92cbf4
- 出典データセット
- uspto-grants-2005_11
- 特許番号
- US06964961B2
反応ノート
読み込み中…